Manchester City visit Leyton Orient for the first time in nearly 60 years this weekend.. The FA Cup fourth round clash sees Orient, chasing promotion in League One, welcome Pep Guardiola’s side to the capital. The Blues are overwhelming favourites to progress to the last 16 of the FA Cup and are likely to make changes for the trip with Real Madrid in town for the Champions League on Tuesday night.. But Guardiola remains hamstrung by a number of fitness concerns with several senior players sidelined. That will limit the number of alterations City make. Here’s the latest from the Etihad treatment room.. Ruben Dias. Injury: Abductor. What we know: Dias has not featured since being replaced at half time in the defeat to PSG. Guardiola confirmed the issue is an abductor problem and there is no timescale on his return, although he is understood to be not far away from featuring.. Potential return date: Leyton Orient (A) February 8. Jeremy Doku. Injury: Unknown. What we know: Doku was one of the stars of the 6-0 win over Ipswich but has not played since.. Potential return date: Leyton Orient (A) February 8. Nathan Ake. Injury: Unknown. What we know: Ake is on the comeback trail from his injury but it is unclear when he will be back.. Potential return date: Leyton Orient (A) February 8. Oscar Bobb. Injury: Fractured leg. What we know: Bobb has not featured for City this season having picked up a serious issue in pre-season. But he is closing in on a comeback in what will be a welcome addition to the squad. Guardiola said last month: “[He is] training with the team partially. That’s good news for us. It was a fractured bone. Now that is healed, he’s fine but good news is he’s back.”. Potential return date: February 2025. Rodri. Injury: Anterior Cruciate Ligament (ACL). What we know: Rodri has sustained a serious knee injury and will be out until the middle of the year. He has spoken of his desire to play again this season, possibly in the Club World Cup.. Potential return date: June 2025