The former US Open champion was unable to make it a hat-trick of British victories on day five after impressive wins for Sonay Kartal and Cameron Norrie.
Saturday’s action will include milestone-chasing Novak Djokovic, reigning women’s champion Barbora Krejcikova and men’s number one Jannik Sinner.
Here, the PA news agency looks back at Friday’s action and previews day six of the Championships.
Raducanu shows she belongs
Emma Raducanu reminded the tennis world what a special talent she is before her Wimbledon hopes were ended with a narrow loss to world number one Aryna Sabalenka.
The 22-year-old played some electrifying tennis under the roof on Centre Court but was unable to apply the finishing touches, eventually going down 7-6 (6) 6-4 after exactly two hours.
Sabalenka was impressed, saying: “She played such incredible tennis and she pushed me really hard to get this win.
“I’m super happy to see her healthy and back on track. I’m pretty sure that she will be back in the top 10 soon.”
Last Britons standing
But home hopes in the singles at Wimbledon are not over.
British number threes Sonay Kartal and Cameron Norrie delighted Court One earlier in the day to reach the fourth round.
Kartal achieved a career first when she dismantled French qualifier Diane Parry to make the last 16 of a grand slam for the first time.
And Norrie followed her lead, knocking out Italy’s Mattia Bellucci in straight sets to set up a clash with Chilean qualifier Nicolas Jarry.
Brit watch
For the first time this week, there will be no British players in action in either of the senior singles draws.
But there are plenty playing in the various doubles tournaments, plus the junior competitions start with 16-year-olds Hannah Klugman and Mika Stojsavljevic – who both appeared in the women’s singles draw this year for the first time – starting their girls’ singles campaigns on Court 12.
Among the doubles players will be Sonay Kartal, who teams up with fellow Briton Jodie Burrage the day before playing her fourth-round singles tie against Anastasia Pavlyuchenkova.
Match of the day
While the outcome of Novak Djokovic against fellow Serb Miomir Kecmanovic may be in little doubt, a victory for the seven-time champion on Saturday would bring up a major milestone.
Djokovic is one victory away from 100 match wins at the Championships, a feat so far managed only by Martina Navratilova and Roger Federer.
The 38-year-old knocked out his Davis Cup team-mate the last time they met – in SW19 three years ago – and has won all three career meetings.
And with Djokovic stating that this tournament is likely to be his best chance of gaining the grand slam title he needs for a record-breaking 25th success, Kecmanovic will require an inspired display to be the last Serb standing.
Order of play
Centre Court (from 1.30pm)
Jannik Sinner (1) v Pedro Martinez
Iga Swiatek (8) v Danielle Collins
Novak Djokovic (6) v Miomir Kecmanovic
Court One (from 1pm)
Mirra Andreeva (7) v Hailey Baptiste
Barbora Krejcikova (17) v Emma Navarro (10)
Ben Shelton (10) v Marton Fucsovics
Weather
Overcast, with a maximum temperature of 22C, according to the Met Office.
